• Product NameEDEM1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total EDEM1 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human EDEM1
• Target NameEDEM1
• Alternative Names    EDEM
• Accession No. Swiss-Prot#:Q92611
  NCBI Gene ID:9695
  Gene Accssion:NP_055489
• UniprotQ92611
• Gene ID9695;
• Concentration 0.8mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20C

• 
  Immunofluorescence:1: 20-100

Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.

• The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47091(EDEM1 Antibody) at dilution 1/20. (Original magnification: ?00)
• The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 47091(EDEM1 Antibody) at dilution 1/20. (Original magnification: ?00)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting