• Product NameNisoldipine
• Brief DescriptionInhibitors
• Purification99.57%
• Biological ActivityNisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.
• Target NameCalcium Channel inhibitor
• CAS No. 63675-72-9
• Calculated MW 388.41
• Formulation C20H24N2O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OCC(C)C
  Pathways:Membrane transporter/Ion channel
  Receptor:L-type Cav1.2
  Boling pt:503.3C
  Melting pt:147-148C
  Solubility:Ethanol: 60 mg/mL warmed (154.47 mM); DMSO: 77 mg/mL (198.24 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Morel N, et al. Br J Pharmacol, 1998, 125(5), 1005-1012.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting