• Product NameSotalol hydrochloride
• Brief DescriptionInhibitors
• Purification99.86%
• Biological ActivitySotalol Hydrochloride is an adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
• Target NameAdrenergic Receptor antagonist; Potassium Channel antagonist
• CAS No. 959-24-0
• Calculated MW 308.82
• Formulation C12H21ClN2O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:Cl.CC(C)NCC(O)C1=CC=C(NS(C)(=O)=O)C=C1
  Pathways:GPCR/G Protein; Membrane transporter/Ion channel
  Receptor:β-adrenergic receptor; Potassium Channel
  Boling pt:443.3C
  Melting pt:218-220C
  Solubility:Water: 62 mg/mL (200.76 mM); DMSO: 62 mg/mL (200.76 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lowe MD, et al. Br J Pharmacol. 2002 Jan;135(2):451-61.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting