• Product NamePramipexole
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPramipexole is a medication indicated for treating Parkinson's disease and restless legs syndrome (RLS). It is also sometimes used off-label as a treatment for cluster headache or to counteract the problems with low libido experienced by some users of SSRI antidepressant drugs. Pramipexole has shown robust effects on pilot studies in bipolar disorder. Pramipexole is classified as a non-ergoline dopamine agonist.
• Target NameDopamine Receptor agonist
• CAS No. 104632-26-0
• Calculated MW 211.33
• Formulation C10H17N3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CCCN[C@H]1CCC2=C(C1)SC(=N2)N
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:D2L; D2L; D3; D4
  Boling pt:
  Melting pt:288-290C
  Solubility:Ethanol: 42 mg/mL (198.74 mM); DMSO: 42 mg/mL (198.74 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kvernmo T, et al. Curr Top Med Chem. 2008;8(12):1049-67.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting