• Product NameSenegenin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityTenuigenin displays antiapoptotic and antioxidative activity in hippocampal neurons due to scavenging of intracellular reactive oxygen species, regulating Bcl-2 family and suppressing caspase-3 activity.
• Target NameCaspase inhibitor
• CAS No. 2469-34-3
• Calculated MW 537.1
• Formulation C30H45ClO6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C[C@@]12CC[C@@H]3[C@@]([C@H]1C[C@@H](C4=C2CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)CCl)(C[C@@H]([C@@H]([C@@]3(C)C(=O)O)O)O)C
  Pathways:Apoptosis; Proteases/Proteasome
  Receptor:Caspase-3
  Boling pt:
  Melting pt:
  Solubility: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Li X, Zhao Y, Liu P,et al.Senegenin Inhibits Hypoxia/Reoxygenation-Induced Neuronal Apoptosis by Upregulating RhoGDIα.Mol Neurobiol. 2015 Dec;52(3):1561-71.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting