• Product NameEndoxifen HCl
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityEndoxifen HCl, the active metabolite of Tamoxifen, ia a potent and selective estrogen receptor antagonist.
• Target NameEstrogen/progestogen Receptor antagonist
• CAS No. 1032008-74-4
• Calculated MW 409.95
• Formulation C25H28ClNO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:cancer
  SMILES:CC/C(=C(\C1=CC=C(C=C1)O)/C2=CC=C(C=C2)OCCNC)/C3=CC=CC=C3.Cl
  Pathways:Endocrinology/Hormones
  Receptor:ER
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 74 mg/mL (180.5 mM)DMSO: 74 mg/mL (180.5 mM)Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chae YJ, et al. Endoxifen, the active metabolite of tamoxifen, inhibits cloned hERG potassium channels. Eur J Pharmacol. 2015 Apr 5;752:1-7.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting