• Product NameCD11b Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JU93-81
• PurificationProA affinity purified
• ApplicationsWB,ICC,IF,IP,IHC,FC
• Species ReactivityHu
• Immunogen DescriptionRecombinant protein
• Alternative Names    antigen CD11b (p170) antibody
  Antigen CD11b p170 antibody
  CD11 antigen like family member B antibody
  CD11 antigen-like family member B antibody
  CD11b antibody
  CD11b/CD18 antibody
  CD49d antibody
  Cell surface glycoprotein MAC-1 subunit alpha antibody
  Complement component 3 receptor 3 subunit antibody
  Complement Component Receptor 3 Alpha antibody
  Complement receptor type 3, alpha subunit antibody
  CR 3 alpha chain (CR3A) antibody
  CR 3 alpha chain antibody
  CR-3 alpha chain antibody
  CR3 antibody
  CR3A antibody
  F730045J24Rik antibody
  Integrin Alpha M antibody
  Integrin alpha M chain antibody
  Integrin alpha-M antibody
  Integrin beta 2 alpha subunit antibody
  Integrin subunit alpha M antibody
  integrin, alpha M (complement component 3 receptor 3 subunit) antibody
  ITAM_HUMAN antibody
  ITGAM antibody
  Leukocyte adhesion receptor MO1 antibody
  Ly-40 antibody
  MAC 1 antibody
  Mac-1a antibody
  MAC1 antibody
  Mac1, alpha subunit antibody
  MAC1A antibody
  Macrophage antigen alpha polypeptide antibody
  MGC117044 antibody
  Mo1, alpha subunit antibody
  MO1A antibody
  Neutrophil adherence receptor alpha M subunit antibody
  Neutrophil adherence receptor antibody
  SLEB6 antibody
  
• Accession No. Swiss-Prot#:P11215
• UniprotP11215
• Gene ID3684;
• Calculated MW 170 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• 
  IHC: 1:50-1:200
  ICC: 1:50-1:200
  
  FC: 1:50-1:100

Integrin αM, also designated complement component receptor-3 α, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

• Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD11b antibody. Counter stained with hematoxylin.
• Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD11b antibody. Counter stained with hematoxylin.
• ICC staining CD11b in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
• Flow cytometric analysis of THP-1 cells with CD11b antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting