• Product NameFKBP52 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JG96-30
• PurificationProA affinity purified
• ApplicationsWB,ICC,IHC,FC
• Species ReactivityHu, Ms
• Immunogen DescriptionRecombinant protein within human FKBP52 aa 1-200.
• Alternative Names    51 kDa FK506-binding protein antibody
  52 kDa FK506 binding protein antibody
  52 kDa FK506-binding protein antibody
  52 kDa FKBP antibody
  59 kDa immunophilin antibody
  FK506 binding protein 4 antibody
  FK506-binding protein 4 antibody
  FKBP 4 antibody
  FKBP 52 antibody
  FKBP 59 antibody
  FKBP-4 antibody
  FKBP-52 antibody
  FKBP4 antibody
  FKBP4_HUMAN antibody
  FKBP51 antibody
  FKBP52 protein antibody
  FKBP59 antibody
  HBI antibody
  Hsp 56 antibody
  HSP binding immunophilin antibody
  HSP-binding immunophilin antibody
  Hsp56 antibody
  Immunophilin FKBP52 antibody
  N-terminally processed antibody
  p52 antibody
  p59 antibody
  p59 protein antibody
  Peptidyl prolyl cis trans isomerase antibody
  Peptidyl-prolyl cis-trans isomerase FKBP4 antibody
  Peptidylprolyl cis trans isomerase antibody
  PPIase antibody
  PPIase FKBP4 antibody
  Rotamase antibody
  T cell FK506 binding protein 59kD antibody
  
• Accession No. Swiss-Prot#:Q02790
• UniprotQ02790
• Gene ID2288;
• Calculated MW 52 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:1,000-1:2,000
  IHC: 1:50-1:200
  ICC: 1:50-1:200
  
  FC: 1:50-1:100

Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.

• Western blot analysis of FKBP52 on 293 (1) and SK-Br-3 (2) cell lysate using anti-FKBP52 antibody at 1/2,000 dilution.
• Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-FKBP52 antibody. Counter stained with hematoxylin.
• Immunohistochemical analysis of paraffin-embedded human esophagus tissue using anti-FKBP52 antibody. Counter stained with hematoxylin.
• Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-FKBP52 antibody. Counter stained with hematoxylin.
• ICC staining FKBP52 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
• ICC staining FKBP52 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
• Flow cytometric analysis of 293T cells with FKBP52 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting