Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis.
[1]DLX3 mutation associated with autosomal dominant amelogenesis imperfecta with taurodontism." Dong J., Amor D., Aldred M.J., Gu T., Escamilla M., MacDougall M.Am. J. Med. Genet. A 133:138-141(2005). [2]The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2004). [3]Genomic structure and functional control of the Dlx3-7 bigene cluster."Sumiyama K., Irvine S.Q., Stock D.W., Weiss K.M., Kawasaki K., Shimizu N., Shashikant C.S., Miller W., Ruddle F.H.Proc. Natl. Acad. Sci. U.S.A. 99:780-785(2002).