• Product NamePlasma kallikrein Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsWB
• Species ReactivityHu Rt
• SpecificityThe antibody detects endogenous level of total Plasma kallikrein polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant Rat Plasma kallikrein protein
• Target NamePlasma kallikrein
• Alternative Names    Fletcher factor Kininogenin Plasma prekallikrein Klkb1 Klk3, Pk
• Accession No. Swiss-Prot#: P14272
• UniprotP14272
• Calculated MW 71kd
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:1000
  

The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.

[1]Gene structure and chromosomal localization of plasma kallikrein.Beaubien G., Rosinski-Chupin I., Mattei M.-G., Mbikay M., Chretien M., Seidah N.G. Biochemistry 30:1628-1635(1991) [2] The cDNA structure of rat plasma kallikrein.Seidah N.G., Ladenheim

• All lanes:Plasma kallikrein antibody at 2ug/ml Lane 1:Hela whole cell lysate Lane 2:rat brain tissue secondary Goat polyclonal to rabbit at 1/10000 dilution predicted band size :71kDa observed band size :71kDa

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting