Promotes cell survival. Potentiates GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. May regulate intracellular calcium pools.
[1] "HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases."Suzuki Y., Demoliere C., Kitamura D., Takeshita H., Deuschle U., Watanabe T.J. Immunol. 158:2736-2744(1997) [