• Product NameTubulin beta-3 chain Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Tubulin beta-3 chain polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Tubulin beta-3 chain protein
• Target NameTubulin beta-3 chain
• Alternative Names    TUBB3
• Accession No. Swiss-Prot#: Q13509
• UniprotQ13509
• Gene ID10381;
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance.

[1] "Cloning and sequencing of human betaIII-tubulin cDNA: induction of betaIII isotype in human prostate carcinoma cells by acute exposure to antimicrotubule agents."Ranganathan S., Dexter D.W., Benetatos C.A., Hudes G.R.Biochim. Biophys. Acta 1395:237-2

• Immunohistochemical analysis of paraffin-embeded human colorectal carcinoma using #42404 at dilution of 1:50.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting