• Product NameAlpha-synuclein Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Alpha-synuclein polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Alpha-synuclein protein
• Target NameAlpha-synuclein
• Alternative Names    Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, PARK1, SNCA
• Accession No. Swiss-Prot#: P37840
• UniprotP37840
• Gene ID6622;
• Calculated MW 16kd
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:1000
  

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

[1] "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." Ueda K., Fukushima H., Masliah E., Xia Y., Iwai A., Yoshimoto M., Otero D.A., Kondo J., Ihara Y., Saitoh T.Proc. Natl. Acad. Sci. U.S.A. 90:11282-11286(

• Alpha-synuclein antibody at 2ug/ml+293T whole cell lysate SecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilution Predicted band size : 16 kDa Observed band size: 55 kDa Additional bands at : 118kDa. We are unsure as to the identity of these extra band.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting