Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
[1] "Isolation and sequence analysis of a full-length cDNA for human M creatine kinase."Perryman M.B., Kerner S.A., Bohlmeyer T.J., Roberts R.Biochem. Biophys. Res. Commun. 140:981-989(1986) [2] "Developmental regulation and tissue-specific expression of