• Product NameSerpin B3 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Serpin B3 polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Serpin B3 protein
• Target NameSerpin B3
• Alternative Names    Protein T4-A, Squamous cell carcinoma antigen 1, SCCA-1, SERPINB3, SCCA, SCCA1
• Accession No. Swiss-Prot#: P29508
• UniprotP29508
• Gene ID6317;
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).

[1]"Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PD."Turato C., Biasiolo A., Pengo P., Frecer V., Quarta S., Fasolato S., Ruvoletto M., Beneduce L., Zuin J., Fassina G., Gatta A., Pontisso P.Exp. Biol. Med. 236:281-290(2011).

• Immunohistochemical analysis of paraffin-embedded human liver cancer using #42534 at dilution of 1:100.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting