• Product NameGRB2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu Rt
• SpecificityThe antibody detects endogenous levels of total GRB2 protein.
• Immunogen Typeprotein
• Immunogen DescriptionFull length fusion protein of human GRB2
• Target NameGRB2
• Alternative Names    ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2
• Accession No. Swiss-Prot#: P62993
  Gene ID: 2885
• UniprotP62993
• Gene ID2885;
• Concentration 1.1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:25-1:100

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using #42705 at dilution 1/20.
• Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #42705 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting