• Product NameGM2A Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total GM2A protein.
• Immunogen Typeprotein
• Immunogen DescriptionFusion protein of human GM2A
• Target NameGM2A
• Alternative Names    SAP-3; GM2-AP
• Accession No. Swiss-Prot#: P17900
  Gene ID: 2760
• UniprotP17900
• Gene ID2760;
• Calculated MW 21kd
• Concentration 0.7mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:25-1:100

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.

• Gel: 12%SDS-PAGE
  Lysate: 40 μg
  Lane: Mouse kidney tissue
  Primary antibody: 1/200 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 2 seconds
• Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using #42969 at dilution 1/25,

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting