• Product NameM6PR Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total M6PR protein.
• Immunogen Typeprotein
• Immunogen DescriptionFusion protein of human M6PR
• Target NameM6PR
• Alternative Names    SMPR; MPR46; CD-MPR; MPR 46; MPR-46
• Accession No. Swiss-Prot#: P20645
  Gene ID: 4074
• UniprotP20645
• Gene ID4074;
• Calculated MW 31kd
• Concentration 1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  Immunohistochemistry: 1:25-1:100

This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.?

• Gel: 8%SDS-PAGE
  Lysate: 40 μg
  Lane 1-2: Hepg2 and lo2 cell
  Primary antibody: 1/400 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 10 seconds
• Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #43050 at dilution 1/20. (Original magnification: ¡Á200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting