• Product NameRBL2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total RBL2 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human RBL2
• Target NameRBL2
• Alternative Names    Rb2; P130
• Accession No. Swiss-Prot#: Q08999
  Gene ID: 5934
• UniprotQ08999
• Gene ID5934;
• Calculated MW 128kd
• Concentration 1.6mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:25-1:100

Retinoblastoma-like protein 2?is a?protein?that in humans is encoded by the?RBL2?gene. Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation.

• Gel: 6%SDS-PAGE
  Lysate: 40 μg
  Lane: Lncap cell
  Primary antibody: 1/200 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 4 minutes

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting