• Product NameSENP6 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SENP6 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human SENP6
• Target NameSENP6
• Alternative Names    SSP1; SUSP1
• Accession No. Swiss-Prot#: Q9GZR1
  Gene ID: 26054
• UniprotQ9GZR1
• Gene ID26054;
• Calculated MW 126kd
• Concentration 1.2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:25-1:100

Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome.

• Gel: 6%SDS-PAGE
  Lysate: 40 μg
  Lane 1-2: Hela cells, K562 cells,
  Primary antibody: 1/450 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 5 minutes
• Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #43143 at dilution 1/20,

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting