• Product NameBRMS1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total BRMS1 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human BRMS1
• Target NameBRMS1
• Alternative Names    breast cancer metastasis suppressor 1; Breast cancer metastasis-suppressor 1; BRMS1; DKFZp564A063
• Accession No. Swiss-Prot#: Q9HCU9
  Gene ID: 25855
• UniprotQ9HCU9
• Gene ID25855;
• Concentration 0.8mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:25-1:100

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

• Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #43231 at dilution 1/20,

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting