• Product NameTPH2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total TPH2 protein.
• Immunogen DescriptionSynthetic peptide of human TPH2
• Target NameTPH2
• Alternative Names    NTPH; ADHD7
• Accession No. Swiss-Prot#: Q8IWU9
  Gene ID: 121278
• UniprotQ8IWU9
• Gene ID121278;
• Calculated MW 56kd
• Concentration 1.2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:20-1:100

This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem.

• Gel: 8%SDS-PAGE
  Lysate: 40 μg
  Lane: Huvec cells
  Primary antibody: 1/300 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 1 minute
• Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #43424 at dilution 1/20.
• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #43424 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting