• Product NameHTR2A Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC Elisa
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total HTR2A protein.
• Immunogen DescriptionSynthetic peptide of human HTR2A
• Target NameHTR2A
• Alternative Names    HTR2; 5-HT2A
• Accession No. Swiss-Prot#: P28223
  Gene ID: 3356
• UniprotP28223
• Gene ID3356;
• Calculated MW 53kd
• Concentration 0.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  Immunohistochemistry:1:25-1:100
  ELISA dilution 5000-10000 

This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene.

• Gel: 8%SDS-PAGELysate: 40 μgLane: Human fetal brain tissue lysatePrimary antibody: 43462(HTR2A Antibody) at dilution 1/200Secondary antibody: Goat anti rabbit IgG at 1/8000 dilutionExposure time: 30 secondsGel: 8%SDS-PAGE
• The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 43462(HTR2A Antibody) at dilution 1/20, on the right is treated with synthetic peptide.
• The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 43462(HTR2A Antibody) at dilution 1/20, on the right is treated with synthetic peptide.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting