• Product NameIGF1R Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total IGF1R protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human IGF1R
• Target NameIGF1R
• Alternative Names    IGFR; CD221; IGFIR; JTK13
• Accession No. Swiss-Prot#: P08069
  NCBI Gene ID: 3480
• UniprotP08069
• Gene ID3480;
• Concentration 0.8mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1: 20-100

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.?

• The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using IGF1R Antibody at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting