• Product NameDES Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC WB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total DES protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human DES
• Target NameDES
• Alternative Names    CSM1; CSM2; LGMD2R
• Accession No. Swiss-Prot#: P17661
  NCBI Gene ID: 1674
• UniprotP17661
• Gene ID1674;
• Calculated MW 54kd
• Concentration 0.8mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1000
  Immunohistochemistry: 1: 20-100

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

• Gel: 8%SDS-PAGE
  Lysate: 40 μg, Lane 1-2: Jurkat and Hela cell lysates,
  Primary antibody:DES antibody at dilution 1/300 dilution,
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
  Exposure time: 10 seconds
• The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using DES Antibody at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting