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DRP1 (Phospho-Ser616) Antibody #12749

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Catalog No. Package Size Price Quantity
12749 100ul $319.00
Availability:Yes
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Description
  • Product NameDRP1 (Phospho-Ser616) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB
  • Species ReactivityHu Ms Rt
  • SpecificityDRP1 (Phospho-Ser616) Antibody detects endogenous levels of DRP1 only when phosphorylated at Ser616
  • Immunogen TypePeptide
  • Immunogen DescriptionA synthesized peptide derived from human DRP1 (Phospho-Ser616)
  • Target NameDRP1
  • ModificationPhospho
  • Alternative Names    DNM1L, DYMPLE, Dynamin 1-like, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, DLP1, Dnm1p/Vps1p-like protein, DVLP, Dynamin-related protein 1, DYNIV-11, DRP1, Dynamin-1-like protein, VPS1, EMPF, HDYNIV
  • Accession No. Swiss-Prot#: O00429
    NCBI Gene ID: 10059
  • UniprotO00429
  • Gene ID10059;
  • Target Species human
  • Calculated MW 79kd
  • Concentration 1.0mg/ml
  • Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20˚C
Application Details

Published Papers

Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsisIn EMBO RepOn2023 Aug 3byChao Fang , Pan Ren et al..PMID:37358015, , (2023),
PMID: 37358015
Ketone Body Improves Neurological Outcomes after Cardiac Arrest by Inhibiting Mitochondrial Fission in Rats. In Oxid Med Cell Longev on 2022 Jul 7 by Yunke Tan, Jie Zhang,et al..PMID:35847595, , (2022),
PMID: 35847595
Levosimendan protects from sepsis-inducing cardiac dysfunction by suppressing inflammation, oxidative stress and regulating cardiac mitophagy via the PINK-1-Parkin pathway in mice. In Ann Transl Med on 2022 Feb by Jian Shi, Yuhong Chen, et al..PMID:35280364, , (2022),
PMID: 35280364
ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension. In Cell Prolif on 2021 Jun by Wei Feng, Jian Wang,et al..PMID: 33948998, , (2021),
PMID: 33948998
View All Published Papers Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis.In Theranostics on 2020 Jan 1; by Dong L, Li P, et al..PMID: 31938063, , (2020),
PMID: 31938063
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.In Int J Biol Sci on 2020 Feb 21; by Deng X, Liu J, et al..PMID:32210728, , (2020),
PMID: 32210728
PyridostigmIne regulates glucose metabolism and mitochondrial homeostasis to reduce myocardial vulnerability to Injury In diabetic mice. In Am J Physiol EndocrInol Metab on 2019 Aug 1 by Yang Y, Zhao M, et al..PMID:31211620, , (2019),
PMID: 31211620
Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features.In Biol Sex Differ. On 2018 Jan 19 by Pesaresi M1, Giatti S et al..PMID:29351809, , (2018),
PMID: 29351809
Please let us know if you have published research using #12749 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep