• Product NameACACB Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityACACB Antibody detects endogenous levels of total ACACB
• Immunogen TypePeptide
• Immunogen DescriptionA synthesized peptide derived from human ACACB
• Target NameACACB
• Alternative Names    ACACB, ACCB, ACC-beta, ACC2, Acetyl-CoA carboxylase 2, Acetyl-CoA carboxylase beta, HACC275
• Accession No. Swiss-Prot#: O00763
  NCBI Gene ID:32
• UniprotO00763
• Gene ID32;
• Calculated MW 270kD
• Concentration 1.0mg/mL
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1：500-2000

 Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008],

• Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting