• Product NameCIR1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CIR1 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human CIR1
• Target NameCIR1
• Alternative Names    CIR
• Accession No. Swiss-Prot:Q86X95
  NCBI Gene ID:9541
  NCBI Protein:NP_004873
• UniprotQ86X95
• Gene ID9541;
• Concentration 1.5mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1: 30-150

May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.

• The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46502(CIR1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
• The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 46502(CIR1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting