• Product NameRecombinant human Vesicle transport through interaction with t-SNAREs homolog 1B
• Brief DescriptionRecombinant Protein
• Host SpeciesE.coli
• PurificationGreater than 90% as determined by SDS-PAGE.
• Immunogen DescriptionExpression Region:7-208aa
  Sequence Info:Cytoplasmic Domain
• Alternative Names    Vesicle transport v-SNARE protein Vti1-like 1Vti1-rp1
• Accession No. Q9UEU0
• UniprotQ9UEU0
• Gene ID10490;
• Calculated MW 39.4 kDa
• Tag Info N-terminal 6xHis-SUMO-tagged
• Target Sequence SSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLL
• Formulation Tris-based buffer50% glycerol
• Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20˚C,-80˚C. The shelf life of lyophilized form is 12 months at -20˚C,-80˚C.
  Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target mbrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.

A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways.Fischer von Mollard G., Stevens T.H.J. Biol. Chem. 273:2624-2630(1998)
Research Topic:Transport

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting