• Product NameAngiotensin II Type 1 Receptor Rabbit mAb
• Clone No.S07-1I6
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthesized peptide derived from human AGTR1
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    AT1;AT1AR;AT1BR;Angiotensin II type-1 receptor
• Accession No. Swiss-Prot:P30556
  GeneID:185
• UniprotP30556
• Gene ID185
• Calculated MW Calculated MW: 41 kDa; Observed MW: 37 kDa
• Formulation Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB 1:1000-1:2000
  

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. (Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, it is able to recognize and internalize the complex formed by secreted ACE2 and SARS-CoV-2 spike protein through DNM2/dynamin 2-dependent endocytosis.

• Western blot analysis of AGTR1 expression in (1) HeLa cell lysate; (2)3T3 cell lysate.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting