• Product NameActivin A Receptor Type IB Rabbit mAb
• Clone No.S08-8D6
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB,IHC,ICC/IF
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic peptide of human Activin A Receptor Type IB
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    ALK4; SKR2; ACTRIB; ACVRLK4
• Accession No. Swiss-Prot:P36896
  GeneID:91
• UniprotP36896
• Gene ID91
• Calculated MW 52kDa
• Concentration 1.2 mg/ml
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Phosphorylates TDP2.

• All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
• All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
• Western blot analysis of ACVR1B expression in U87-MG cell lysate.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting