• Product NameIntegrin alpha 2 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S06-7A5
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityHuman,Mouse
• Immunogen DescriptionA synthetic peptide of human Integrin alpha 2
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2
• Accession No. Swiss-Prot:P17301
  GeneID:3673
• UniprotP17301
• Gene ID3673
• Calculated MW Calculated MW: 129 kDa; Observed MW: 150 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/2000-1/10000;

Swiss-Prot Acc.P17301.Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.(Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A.

• Western blot detection of Integrin alpha 2 in Hela cell lysates using Integrin alpha 2 Rabbit mAb(1:1000 diluted).Predicted band size:129kDa.Observed band size:150kDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting