• Product NameSHP1 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S06-4C8
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB IHC
• Species ReactivityHuman
• Immunogen DescriptionA synthetic peptide of human SHP1
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1
• Accession No. Swiss-Prot:P29350
  GeneID:5777
• UniprotP29350
• Gene ID5777
• Calculated MW Calculated MW: 68 kDa; Observed MW: 68 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000-1/5000; IHC: 1/200-1/500;

Swiss-Prot Acc.P29350.Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.

• Western blot detection of SHP1 in Jurkat cell lysates using SHP1 Rabbit mAb(1:500 diluted).Predicted band size:68kDa.Observed band size:68kDa.
• Immunohistochemistry of SHP1 in paraffin-embedded Human tonsil using SHP1 Rabbit mAb at dilution 1/50

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting