• Product NameTDP 43 Rabbit mAb
• Clone No.S02-2A8
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB,IHC,ICC/IF,IP,FC
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthesized peptide derived from human TDP43
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    ALS10; TDP-43
• Accession No. Swiss-Prot:Q13148
  GeneID:23435
• UniprotQ13148
• Gene ID23435
• Calculated MW Calculated MW: 45 kDa; Observed MW: 45 kDa
• Concentration 0.8 mg/ml
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:200

TDP43 (TAR DNA-binding protein 43) is involved in transcriptional regulation and exon splicing. While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

• All lanes use the Antibody at 1:4K dilution for 1 hour at room temperature.
• All lanes use the Antibody at 1:4K dilution for 1 hour at room temperature.
• Western blot analysis of TDP43 expression in K562 cell lysate.
• All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting