• Product NameNME2 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S08-1C1
• IsotypeIgG
• PurificationAffinity Purified
• ApplicationsWB IHC
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic peptide of human NME2
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    PUF; NDKB; NDPKB; NM23B; NDPK-B; NM23-H2
• Accession No. Swiss-Prot:P22392
  GeneID:4831
• UniprotP22392
• Gene ID4831
• Calculated MW Calculated MW:17 kDa,Observed MW:17 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000 IHC: 1/50

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Negatively regulates Rho activity by interacting with AKAP13/LBC (PubMed:15249197). Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752, PubMed:19435876).

• Western blot detection of NME2 in U2OS,C6,Ramos using NME2 Rabbit mAb(1:1000 diluted)
• Immunohistochemical of NME2 in Human lung cancer tissue using NME2 antibody at dilution 1/50

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting