• Product NameTuberin Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S06-0D3
• IsotypeIgG
• PurificationAffinity Purified
• ApplicationsWB IHC
• Species ReactivityHuman
• Immunogen DescriptionA synthetic peptide of human Tuberin
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin;TSC4
• Accession No. Swiss-Prot:P49815
  GeneID:7249
• UniprotP49815
• Gene ID7249
• Calculated MW Calculated MW:201 kDa,Observed MW:201 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000 IHC: 1/20

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Western blot detection of Tuberin in Hela,A549,MCF-7,293T cell lysates using Tuberin Rabbit mAb(1:1000 diluted).Predicted band size:201kDa.Observed band size:201kDa.
• Immunohistochemical of Tuberin in Human hepatic carcinoma tissue using Tuberin antibody at dilution 1/50

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting