• Product NameATM Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB IHC ICC/IF FC
• Species ReactivityHuman
• SpecificityATM Antibody detects endogenous levels of total ATM
• Immunogen DescriptionA synthesized peptide derived from human ATM
• Alternative Names    A-T, mutated; Ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; EC 2.7.11.1; kinase ATM; Serine-protein kinase ATM
• Accession No. Uniprot:Q13315
• UniprotQ13315
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:200 FC 1:50

• ATM encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1.

ATM encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1.

• Western blot analysis of ATM expression in HeLa cell lysate.
• Immunohistochemical analysis of paraffin-embedded human breast cancer, using ATM Antibody.
• Immunofluorescent analysis of Hela cells, using ATM Antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting