• Product NamehnRNP K Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB IHC ICC/IF IP
• Species ReactivityHuman Mouse Rat
• SpecificityhnRNP K Antibody detects endogenous levels of hnRNP K
• Immunogen DescriptionA synthesized peptide derived from human hnRNP K
• Alternative Names    65 kDa phosphoprotein; CSBP; TUNP; HNRNPK; HNRPK; DC-stretch binding protein; hnRNP-K;
• Accession No. Uniprot:P61978
• UniprotP61978
• Calculated MW 60kDa
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:5000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:20

• Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor.

Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor.

• Western blot analysis of hnRNP K expression in Jurkat cell lysate.
• Immunohistochemical analysis of paraffin-embedded human colon, using hnRNP K Antibody.
• All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting