• Product NameIKK alpha+beta Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB ICC/IF IP
• Species ReactivityHuman Mouse Rat
• SpecificityIKK alpha+beta Antibody detects endogenous levels of IKK alpha+beta
• Immunogen DescriptionA synthesized peptide derived from human IKK alpha+beta
• Alternative Names    I-kappa-B kinase 2; I-kappa-B-kinase beta; IKBKB; IKK-B; IKK-beta; IKK2; IKKB;
• Accession No. Uniprot:O15111/O14920
• UniprotO15111/O14920
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:500~1:1000 ICC/IF 1:50~1:100 IP 1:50

• IKK-beta a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.

IKK-beta a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.

• Western blot analysis of IKK alpha+beta expression in (1) A431 cell lysate; (2) 293T cell lysate; (3) Mouse kidney lysate.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting