• Product NameCaspase-8 Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB IHC ICC/IF
• Species ReactivityHuman
• SpecificityCaspase-8 Antibody detects endogenous levels of Caspase-8
• Immunogen DescriptionA synthesized peptide derived from human Caspase-8
• Alternative Names    Caspase 8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; FADD-homologous ICE/ced-3-like protease; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH; Caspase-8 subunit p18; CAP4;
• Accession No. Uniprot:Q14790
• UniprotQ14790
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

• Caspases are a family of cytosolic aspartate specific cysteine proteases. Involved in the activation cascade of caspases responsible for apoptosis execution. Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7.

Caspases are a family of cytosolic aspartate specific cysteine proteases. Involved in the activation cascade of caspases responsible for apoptosis execution. Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7.

• Western blot analysis of Caspase-8 expression in HeLa cell lysate.
• Immunohistochemical analysis of paraffin-embedded human uterus, using Caspase-8 Antibody.
• Immunofluorescent analysis of Hela cells, using Caspase-8 Antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting