• Product NameCaspase-1 Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB IP
• Species ReactivityHuman Mouse Rat
• SpecificityCaspase-1 Antibody detects endogenous levels of total Caspase-1
• Immunogen DescriptionA synthesized peptide derived from Caspase-1
• Alternative Names    CASP-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; caspase-1;
• Accession No. Uniprot:P29466
• UniprotP29466
• Concentration 2mg/ml
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:500~1:2000 IP 1:50

• Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

• Western blot analysis of Caspase-1 expression in NIH/3T3 cell lysate.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting