• Product NameRASSF6 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB
• Species ReactivityHu
• SpecificityAt least four isoforms of RASSF6 are known to exist. RASSF6 antibody is predicted to not cross-react with other RASSF family members.
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 14 amino acid peptide near the center of human RASSF6.
• Target NameRASSF6
• Alternative Names    Ras association, RalGDS, AF-6, domain family 6
• Accession No. Swiss-Prot:Q6ZTQ3
  Gene ID:166824
• UniprotQ6ZTQ3
• Gene ID166824;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. RASSF6 (Ras association (RalGDS/AF-6) domain family member 6), a member of RASSF family, acts as a Ras effector protein / tumor suppressor. RASSF6 contains one Ras-associating domain and one SARAH domain. It is involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. Defects in RASSF6 may facilitate viral NFκ-B pathway and may play a vital role in infection.

• Western blot analysis of RASSF6 in 293 cell lysate with RASSF6 antibody at 1 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting