• Product NameIL23R Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• ApplicationsELISA WB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total IL23R protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 31-227 amino acids of Human Interleukin-23 receptor
• Target NameIL23R
• Alternative Names    Interleukin-23 receptor
• Accession No. Swiss-Prot:Q5VWK5
  Gene ID:149233;
• UniprotQ5VWK5
• Gene ID149233;
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C/1 year

• Predicted MW: 72kd
  ELISA: 1:500-1:5000
  Western blotting: 1:500-1:2000
  Immunohistochemistry: 1:5-1:20

The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

• Gel: 8%SDS-PAGE
  Lysate: 40 µg Human sigmoid tissue lysate
  Primary antibody: 1/300 dilution
  Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution
  Exposure time: 30 seconds
• The image on the left is immunohistochemistry of paraffin-embedded Human rectal cancer tissues using 31023 (IL23R Antibody) at dilution 1/10, on the right is treated with the fusion protein.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting