• Product NameCBX2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• ApplicationsELISA WB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous level of total CBX2 protein.
• Immunogen TypeRecombinant protein
• Immunogen DescriptionFull length fusion protein
• Target NameCBX2
• Alternative Names    chromobox homolog 2, M33, CDCA6, SRXY5
• Accession No. Swiss-Prot:Q14781
  Gene ID:84733;
• UniprotQ14781
• Gene ID84733;
• Concentration 0.72mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C/1 year

• Predicted MW: 23kd
  ELISA: 1:1000-1:5000
  Western blotting: 1:500-1:2000

This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

• Gel: 12+10%SDS-PAGE
  Lane1: Human ovarian cancer tissue lysate
  Lane2: Mouse heart tissue lysate
  Lysates: 30ug per lane
  Primary antibody: 1/350 dilution
  Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
  Exposure time: 20 seconds
  

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting