• Product NameIGF2BP2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• ApplicationsELISA WB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total IGF2BP2 protein.
• Immunogen TypeRecombinant protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 65-169 amino acids of human insulin-like growth factor 2 mRNA binding protein 2
• Target NameIGF2BP2
• Alternative Names    insulin-like growth factor 2 mRNA binding protein 2, p62, IMP2, IMP-2, VICKZ2
• Accession No. Swiss-Prot:Q9Y6M1
  Gene ID:10644;
• UniprotQ9Y6M1
• Gene ID10644;
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C/1 year

• Predicted MW: 66kd
  ELISA: 1:1000-1:5000
  Western blotting: 1:200-1:1000

This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.? May regulate translation of target mRNAs.

• Gel: 8%SDS-PAGE
  Lane1: Human liver cancer tissue lysate
  Lane2: Human ovarian cancer tissue lysate
  Lysates: 40 ug per lane
  Primary antibody: 1/300 dilution
  Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
  Exposure time: 2 minutes
  
  

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting