• Product NamePARK7 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• ApplicationsELISA WB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total PARK7 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFull length fusion protein
• Target NamePARK7
• Alternative Names    parkinson protein 7, DJ1, DJ-1
• Accession No. Swiss-Prot:Q99497
  Gene ID:11315;
• UniprotQ99497
• Gene ID11315;
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C/1 year

• Predicted MW: 20kd
  ELISA: 1:1000-1:5000
  Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:50-1:200

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

• Gel: 8%+10% SDS-PAGE
  Lysate: 60 µg Hela cell lysate
  Primary antibody: 1/300dilution
  Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
  Exposure time: 2 minutes
• The image on the left is immunohistochemistry of paraffin-embedded human lung cancer tissue using 31108 (PARK7 Antibody) at dilution 1/25, on the right is treated with the fusion protein.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting