• Product NameCBR1 Monoclonal Antibody
• Host SpeciesMouse
• ClonalityMonoclonal
• Clone No.2C9-B12-C4
• IsotypeIgG1
• PurificationAffinity purified
• ApplicationsWB ICC
• Species ReactivityHu
• SpecificityThis antibody detects endogenous levels of CBR1,and does not cross-react with related proteins.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionPurified recombinant human CBR1 protein fragments expressed in E.coli
• Target NameCBR1
• Alternative Names    15 hydroxyprostaglandin dehydrogenase [NADP+]; 15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1;
• Accession No. Uniprot: P16152

  Gene ID: 873

• UniprotP16152
• Gene ID873;
• SDS-PAGE MW 30kd
• Formulation Purified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide,50% glycerol.
• Storage store at -20˚C

• Western blotting: 1:1000

  Immunocytochemistry: 1:100

 NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.

• Immunocytochemistry stain of Hela using CBR1 antibody (1:100).
• Western blot detection of CBR1 in Hela,A431 & MDA-MB-468 cell lysates using CBR1 antibody(1:1000 diluted).Predicted band size:30KDa,Observed band size:30KDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting