• Product NameFHL2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous level of total FHL2 protein.
• Immunogen TypePeptide-KLH
• Immunogen DescriptionPeptide sequence around aa.16~28 (I-L-R-E-E) derived from Human FHL2.
• Target NameFHL2
• Alternative Names    SLIM3; AAG11; FHL-2; DRAL; aging-associated gene 11
• Accession No. Swiss-Prot: Q14192 NCBI Protein: NP_001034581.1
• UniprotQ14192
• Gene ID2274;
• SDS-PAGE MW 32kd
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20°C

•  Western blotting: 1:500～1:1000

 May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. 

• Western blot analysis of extracts from mouse brain tissue using FLH2 Antibody  #21692.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting