• Product NameBTK Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total BTK protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant fusion protein of human BTK (NP_000052.1).
• Target NameBTK
• Alternative Names    AGMX1;AT;ATK;BPK;IMD1;PSCTK1;XLA;BTK
• Accession No. Uniprot:Q06187
  GeneID:695
• UniprotQ06187
• Gene ID695
• SDS-PAGE MW Refer to Figures
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IHC 1:50 - 1:100

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Immunohistochemistry of paraffin-embedded rat spleen using BTK antibody.
• Immunohistochemistry of paraffin-embedded mouse spleen using BTK antibody.
• Immunohistochemistry of paraffin-embedded mouse brain using BTK antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting