• Product NameSERPING1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB,IF
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total SERPING1 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human SERPING1.
• Target NameSERPING1
• Alternative Names    C1IN; C1NH; HAE1; HAE2; C1INH
• Accession No. Swiss-Prot:P05155
  NCBI Gene ID:710
• UniprotP05155
• Gene ID710;
• SDS-PAGE MW 55KD
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:1000 - 1:2000
  IF 1:50 - 1:200

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

• Immunofluorescence analysis of NIH/3T3 cells using C1 Inactivator at dilution of 1:100. Blue: DAPI for nuclear staining.
• Western blot analysis of extracts of various cell lines, using C1 Inactivator at 1:1000 dilution.
• Immunofluorescence analysis of C6 cells using C1 Inactivator at dilution of 1:100. Blue: DAPI for nuclear staining.
• Immunofluorescence analysis of HeLa cells using C1 Inactivator at dilution of 1:100. Blue: DAPI for nuclear staining.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting